Your Hospital Is Leaking $200K a Year. Let's Plug It.

A turn-key orphan drug system that finds your hidden savings, captures every dollar, and stays current every quarter—so your team can focus on patient care instead of spreadsheets.

Unlock Your $200K

Is Your 340B Orphan Drug Program Leaving Money on the Table?

Burning 30+ hours every quarter on research that's outdated by the time you finish
Drowning in spreadsheets that create more confusion than clarity—and cost you real dollars
Confused by manufacturer discretionary pricing and missing opportunities because the rules keep changing
Watching six figures slip through the cracks because generic tools can't keep up with quarterly changes

Show Me the Money

Finally: A Turn-Key Orphan Drug System Built for Hospitals Like Yours

After 11+ years and $500M+ in orphan drug savings for hospitals nationwide, I built the system I wish existed when I started.

It's not a generic tool. It's not a one-size-fits-all spreadsheet.

It's a turn-key orphan drug engine designed specifically for Critical Access Hospitals, Rural Referral Centers, and Sole Community Hospitals—the facilities most affected by the October 2015 ruling.

Every component adapts to YOUR facility, works within YOUR existing workflows, and stays current as orphan drug designations and manufacturer pricing change quarterly.

Three Pillars:

Tailored Orphan Drug Lists

Custom-built for your facility type and case mix

Seamless Split Billing Integration

Upload-ready files—no disruption to your workflow

Automated Quarterly Updates

Never fall behind on manufacturer pricing changes

Claim Your Savings

Why This System Works—Straight from the Expert!

I'm Dr. Lisa Nezneski, PharmD, BCPS—and I've spent 40+ years in healthcare with the last 11+ years focused exclusively on 340B orphan drugs.

I've helped hospitals capture over $500 million in orphan drug savings. I know which manufacturers offer discretionary pricing, which ones just changed their rules last week, and exactly how to configure your split-billing software to capture every eligible dollar.

I bring a heart-centered approach to each client—because your hospital deserves a partner who understands your unique challenges, not just another vendor.

Let's Talk Savings

Here's What Changes When You Partner With Us

Never Miss Another Dollar: Automatic orphan drug tracking means zero slip-through-the-cracks revenue. Every eligible purchase. Every quarter. Captured.
Discover Your "Found Money": Most clients uncover $50K–$200K in missed savings in their first quarter. How much is sitting untouched in yours?
Quarterly Intel Drops: Get manufacturer pricing changes the moment they happen—not months later when it's too late. Stay ahead while competitors play catch-up.

Seamless Split-Billing Integration: Upload-ready files that work with your existing software. No disruption. No learning curve. Just results.
Get 30+ Hours Back Every Quarter: Imagine your staff focusing on patient care instead of spinning their wheels on labor-intensive research that's outdated by next month.
Expert Support at Every Step: Direct access to a 340B orphan drug specialist—not a call center, not a chatbot. Real answers. Real results. A true partnership.

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Why Hospitals Trust 340B Orphan Drug Solutions

This isn't a side hustle. It's my life's

work.

We don't hand you a list and disappear. We handle the heavy lifting—customized drug lists, split-billing integration, quarterly updates, job aids, and ongoing support. You focus on patients.

CAH, RRC, or SCH—each gets a custom solution that fits your specific case mix, patient population, and split-billing software.

Most clients see tangible results within the first quarter. The "found money" typically pays for the service many times over.

See What You're Missing

Frequently Asked Questions

Questions? Answers.

Who qualifies for 340B Orphan Drug Support?

Critical Access Hospitals (CAH), Rural Referral Centers (RRC), Sole Community Hospitals (SCH), and Free-Standing Cancer Hospitals affected by the October 2015 ruling on orphan drug exclusions.

Does the program cover all 50 states?

Yes. We work with qualifying hospitals nationwide.

Will my information be confidential?

Absolutely. Your facility data, savings figures, and program details remain strictly confidential.

How does this work?

We start with a discovery call to understand your current situation and case mix. From there, we build your custom orphan drug list, integrate with your split-billing system, and provide quarterly updates with ongoing expert support. It's truly turn-key.

Isn’t this a one size fits all?

The opposite. Every deliverable is customized to your facility type, your patient population, your software, and your specific challenges. It's not just a list—it's a partnership.

Do you have a service to help with implementation?

Most clients see ROI within the first quarter. We often identify "found money" from missed opportunities right away.

Let’s Find My Money

Real Results from Real Hospitals

Our clients are at the heart of everything we do. Their feedbacks reflect our commitment to providing compassionate care, trusted expertise, and personalized attention.

"I was spending nearly 30 hours each quarter trying to track orphan drug designations and manufacturer discounts. Dr. Nezneski's service cut that down to just a few hours of review time. The automated updates and custom reports have helped us capture an additional $280,000 in savings this year alone."

Sarah C., PharmD

CEO AND FOUNDER

"As a critical access hospital, we were struggling to keep up with manufacturer discretionary pricing. 340B Orphan Drug Solutions provided us with clear, actionable data that integrated perfectly with our split billing system. Their quarterly updates ensure we never miss an opportunity for savings."

Michael T.

340B Program Manager

"The level of detail and customization in their service is outstanding. Dr. Nezneski worked directly with our team to understand our specific challenges and created a solution that works seamlessly with our existing processes. We've reduced audit preparation time by 75% while increasing our capture rate."

Jennifer M., RPh

System Pharmacy Director

"What impressed me most was how quickly we saw results. Within the first quarter, we identified several missed opportunities and captured over $125,000 in additional savings. The ongoing support and expertise have been invaluable for our rural health system."

Robert K.

Chief Pharmacy Officer

"Managing orphan drugs across multiple facilities was a constant challenge until we partnered with 340B Orphan Drug Solutions. Their system has streamlined our processes and eliminated the confusion between facilities. The ROI was clear within the first month."

Patricia O., MBA, RPh

Corporate Director of Pharmacy

"The peace of mind alone is worth the investment. Knowing our orphan drug program is optimized and compliance-ready lets us focus on patient care. Dr. Nezneski's expertise in both 340B and orphan drugs has been a game-changer for our organization."